Hairy Projections on Non Hairy Cells- A Case Report
Published: August 1, 2021 | DOI: https://doi.org/10.7860/JCDR/2021/49864.15289
Rhituparna Das, Sriranjan Mukherjee, Moumita Sengupta
1. Junior Resident, Department of Pathology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
2. Junior Resident, Department of Pathology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
3. Associate Professor, Department of Pathology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.
Correspondence
Dr. Moumita Sengupta,
1185, Chakgaria, Flat-A11, Sneha Neer Apartment, PO Panchasayar, Kolkata-700094, West Bengal, India.
E-mail: moumitasengupta83@gmail.com
Adult T-Cell Leukaemia/Lymphoma (ATLL) is a mature T-cell neoplasm. It is caused by human retrovirus Human T-cell Lymphotropic Virus Type 1(HTLV-1). The neoplastic cells after monoclonal integration begin to express T-cell associated antigens namely CD2, CD3 and CD5. These leukaemic cells are highly pleomorphic in light microscopic appearance and also they have a highly variable clinical presentation ranging from acute to lymphomatous to chronic to smouldering. There is a chance of missed or miss diagnosis due to their morphological and clinical heterogeneity and specialised test like immunophenotyping or flow cytometry is essential for exact categorisation. Authors hereby, report a case of 45-year-old female patient suffering from ATLL whose peripheral smear showed leukaemic cells with unusual hairy projections resembling hairy cell leukaemia posing diagnostic dilemma.
[
FULL TEXT ] | [ PDF]